Liaobin Chen Selected Research

Developmental Bone Diseases (Bone Dysplasia)

1/2022	The miR-98-3p/JAG1/Notch1 axis mediates the multigenerational inheritance of osteopenia caused by maternal dexamethasone exposure in female rat offspring.
1/2021	Prenatal caffeine exposure caused H-type blood vessel-related long bone dysplasia via miR375/CTGF signaling.
3/2020	Subchondral bone dysplasia mediates susceptibility to osteoarthritis in female adult offspring rats induced by prenatal caffeine exposure.
2/2020	Egr1/p300/ACE signal mediates postnatal osteopenia in female rat offspring induced by prenatal ethanol exposure.
1/2020	Subchondral bone dysplasia partly participates in prenatal dexamethasone induced-osteoarthritis susceptibility in female offspring rats.
12/2018	Intrauterine Programming of Glucocorticoid-Insulin-Like Growth Factor-1 Axis-Mediated Developmental Origin of Osteoporosis Susceptibility in Female Offspring Rats with Prenatal Caffeine Exposure.
10/2017	Glucocorticoid mediates prenatal caffeine exposure-induced endochondral ossification retardation and its molecular mechanism in female fetal rats.

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Liaobin Chen Research Topics

Disease

21	Osteoarthritis 07/2022 - 10/2010
17	Fetal Growth Retardation (Intrauterine Growth Retardation) 01/2021 - 11/2012
9	Infections 06/2022 - 11/2007
9	Osteoporosis 01/2022 - 11/2012
7	Developmental Bone Diseases (Bone Dysplasia) 01/2022 - 10/2017
6	Body Weight (Weight, Body) 01/2022 - 01/2014
6	Hypercholesterolemia 01/2019 - 10/2015
6	Metabolic Syndrome (Dysmetabolic Syndrome X) 12/2015 - 01/2012
4	Metabolic Bone Diseases (Osteopenia) 01/2022 - 01/2019
4	Wounds and Injuries (Trauma) 12/2021 - 05/2015
3	Non-alcoholic Fatty Liver Disease 01/2019 - 01/2014
2	Inflammation (Inflammations) 11/2021 - 01/2021
2	Necrosis 07/2020 - 01/2017
2	Dyslipidemias (Dyslipidemia) 01/2016 - 01/2014
1	Weight Gain 06/2022
1	Pigmented Villonodular Synovitis 05/2022
1	Mitochondrial Diseases (Mitochondrial Disease) 01/2022
1	Arthralgia (Joint Pain) 01/2022
1	Premature Obstetric Labor (Premature Labor) 12/2021
1	Hypoxia (Hypoxemia) 11/2021
1	Hypoalbuminemia 09/2021
1	Venous Thromboembolism 09/2021
1	Bone Diseases (Bone Disease) 01/2021
1	Osteonecrosis (Kienbock's Disease) 01/2021
1	Osteosarcoma (Osteogenic Sarcoma) 01/2021
1	Osteolysis 01/2021
1	Liver Diseases (Liver Disease) 10/2020
1	Chronic Disease (Chronic Diseases) 01/2020
1	Tibial Fractures (Fracture, Tibial) 07/2019
1	Cardiovascular Diseases (Cardiovascular Disease) 01/2019
1	Pain (Aches) 10/2018
1	Cysts 04/2018
1	Ganglion Cysts (Ganglion) 04/2018
1	Stress Fractures (Stress Fracture) 03/2018
1	Surgical Wound Infection 03/2018
1	Knee Osteoarthritis 12/2017

Drug/Important Bio-Agent (IBA)

17	Caffeine (No Doz)FDA LinkGeneric 07/2022 - 01/2012
10	Ethanol (Ethyl Alcohol)IBA 02/2022 - 01/2014
9	GlucocorticoidsIBA 07/2022 - 10/2017
8	Dexamethasone (Maxidex)FDA LinkGeneric 01/2022 - 10/2015
8	CholesterolIBA 01/2021 - 10/2015
7	CorticosteroneIBA 07/2022 - 01/2014
6	Nicotine FDA Link 01/2020 - 05/2013
5	Vancomycin FDA LinkGeneric 06/2022 - 01/2021
5	Anti-Bacterial Agents (Antibiotics)IBA 06/2022 - 11/2007
4	Glucose (Dextrose)FDA LinkGeneric 11/2021 - 01/2014
4	Insulin (Novolin)FDA Link 12/2018 - 10/2010
4	Insulin-Like Growth Factor I (IGF-1)IBA 10/2018 - 10/2010
3	SteroidsIBA 01/2021 - 05/2015
3	Proteins (Proteins, Gene)FDA Link 04/2018 - 10/2010
3	LipidsIBA 10/2016 - 01/2014
2	Aggrecans (Aggrecan)IBA 07/2022 - 04/2018
2	Pravastatin (Pravachol)FDA LinkGeneric 02/2022 - 01/2021
2	PowdersIBA 01/2022 - 12/2021
2	Biomarkers (Surrogate Marker)IBA 01/2021 - 01/2021
2	Insulin-Like PeptidesIBA 10/2020 - 03/2016
2	Histones (Histone)IBA 01/2019 - 10/2018
2	Proteoglycans (Proteoglycan)IBA 12/2014 - 10/2014
1	EnzymesIBA 07/2022
1	Oxidoreductases (Dehydrogenase)IBA 01/2022
1	Lactic Acid (Lactate)FDA LinkGeneric 01/2022
1	SolutionsIBA 01/2022
1	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2022
1	morusinIBA 12/2021
1	CateninsIBA 12/2021
1	Facilitative Glucose Transport Proteins (Glucose Transporter)IBA 11/2021
1	Cisplatin (Platino)FDA LinkGeneric 01/2021
1	Zoledronic Acid (Zometa)FDA Link 01/2021
1	InterleukinsIBA 01/2021
1	Hydrocortisone (Cortisol)FDA LinkGeneric 01/2021
1	Competitive Endogenous RNAIBA 03/2020
1	ReninIBA 02/2020
1	AngiotensinsIBA 02/2020
1	enhanced green fluorescent proteinIBA 07/2019
1	Carrier Proteins (Binding Protein)IBA 12/2018
1	Glucocorticoid Receptors (Glucocorticoid Receptor)IBA 12/2018
1	Hydrocodone (Dihydrocodeinone)FDA LinkGeneric 10/2018
1	Morphine (MS Contin)FDA LinkGeneric 10/2018
1	Acetaminophen (Paracetamol)FDA LinkGeneric 10/2018
1	CollagenIBA 04/2018
1	PapainIBA 01/2018

Therapy/Procedure

5	Arthroplasty 06/2022 - 01/2021
5	Knee Replacement Arthroplasty (Total Knee Replacement) 01/2022 - 05/2015
4	Debridement 06/2022 - 03/2018
3	Prostheses and Implants (Prosthesis) 12/2021 - 05/2015
3	Ovariectomy (Oophorectomy) 12/2021 - 01/2020
2	Synovectomy 05/2022 - 03/2018
2	Anterior Cruciate Ligament Reconstruction 01/2022 - 01/2022
2	Reoperation 12/2021 - 01/2021
2	Length of Stay 09/2021 - 05/2015
2	Drug Therapy (Chemotherapy) 01/2021 - 01/2017
2	Hip Replacement Arthroplasty (Total Hip Replacement) 05/2015 - 08/2012
1	Radiotherapy 05/2022
1	Replacement Arthroplasty 01/2022
1	Intraperitoneal Injections 01/2022
1	Aftercare (After-Treatment) 01/2022
1	Adjuvant Chemotherapy 01/2021
1	Decompression 07/2020
1	Meniscectomy 03/2018
1	Intra-Articular Injections 01/2018